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Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy.

Emerging infectious diseases - 1 Dec 2021

Baj Andreina, Novazzi Federica, Pasciuta Renee, Genoni Angelo, Ferrante Francesca Drago, Valli Marilena, Partenope Michele, Tripiciano Rosalia, Ciserchia Andrea, Catanoso Giuseppe, Focosi Daniele, Maggi Fabrizio

Abstract excerpt

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11-July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.

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Identifiers

PMID: 34499599
DOI: 10.3201/eid2712.211792
PMCID: PMC8632179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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