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Whole Genome Sequencing Assessing Impact of Diabetes Mellitus on Tuberculosis Mutations and Type of Recurrence in India.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 14 Sept 2022

Mave Vidya, Chen Liang, Ranganathan Uma Devi, Kadam Dileep, Vishwanathan Vijay, Lokhande Rahul, S Siva Kumar, Kagal Anju, Pradhan Neeta N, Shivakumar Shri Vijay Bala Yogendra, Paradkar Mandar S, Deshmukh Sona, Tornheim Jeffrey A, Kornfeld Hardy, Farhat Maha, Gupta Amita, Padmapriyadarsini Chandrasekaran, Gupte Nikhil, Golub Jonathan E, Mathema Barun, Kreiswirth Barry N

Abstract excerpt

BACKGROUND: Evidence describing the impact of diabetes mellitus (DM) on the recurrence and mutation rate of Mycobacterium tuberculosis (Mtb) is limited. METHODS: This study was nested in 3 cohort studies of tuberculosis (TB) patients with and without DM in India. Paired Mtb isolates recovered at baseline and treatment failure/recurrence underwent whole genome sequencing. We compared acquisition of...

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Identifiers

PMID: 34984435
DOI: 10.1093/cid/ciab1067
PMCID: PMC9477453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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