Article
Whole genome sequencing analysis to evaluate the influence of T2DM on polymorphisms associated with drug resistance in M. tuberculosis.
BMC genomics - 24 Jun 2022
Bermudez-Hernández Gustavo Adolfo, Pérez-Martínez Damián Eduardo, Madrazo-Moya Carlos Francisco, Cancino-Muñoz Irving, Comas Iñaki, Zenteno-Cuevas Roberto
Abstract excerpt
BACKGROUND: Type 2 diabetes mellitus (T2DM) has been associated with treatment failure, and the development of drug resistance in tuberculosis (TB). Also, whole-genome sequencing has provided a better understanding and allowed the growth of knowledge about polymorphisms in genes associated with drug resistance. Considering the above, this study analyzes genome sequences to evaluate the influence of type 2...
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