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Article

microRNA-155-3p delivered by M2 macrophages-derived exosomes enhances the progression of medulloblastoma through regulation of WDR82

4 Jan 2022

Abstract excerpt

OBJECTIVE: Exosomes, membranous nanovesicles, naturally bringing proteins, mRNAs, and microRNAs (miRNAs), play crucial roles in tumor pathogenesis. This study was to investigate the role of miR-155-3p from M2 macrophages-derived exosomes (M2-Exo) in promoting medulloblastoma (MB) progression by mediating WD repeat domain 82 (WDR82). METHODS: miR-155-3p expression was detected by RT-qPCR. The relationship of...

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PMID: 34983581
DOI: 10.1186/s12967-021-03156-y

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