Plasmodium falciparum histidine rich protein 2 (pfhrp2): an additional genetic marker suitable for anti-malarial drug efficacy trials.

doi:10.1186/s12936-021-04014-4

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Article

Plasmodium falciparum histidine rich protein 2 (pfhrp2): an additional genetic marker suitable for anti-malarial drug efficacy trials.

Malaria journal - 4 Jan 2022

Atroosh Wahib M, Lau Yee-Ling, Snounou Georges, Azzani Meram, Al-Mekhlafi Hesham M

Abstract excerpt

BACKGROUND: Genotyping of the three Plasmodium falciparum polymorphic genes, msp1, msp2 and glurp, has been adopted as a standard strategy to distinguish recrudescence from new infection in drug efficacy clinical trials. However, the suitability of a particular gene is compromised in areas where...

Topics

Antigens, Protozoan
Antimalarials
Genetic Markers
Genotype
Humans
Malaria, Falciparum
Plasmodium falciparum
Protozoan Proteins

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