Article
Worldwide diversity, association potential, and natural selection in the superimposed taste genes, CD36 and GNAT3.
Chemical senses - 1 Jan 2022
Wooding Stephen P, Ramirez Vicente A
Abstract excerpt
CD36 and GNAT3 mediate taste responses, with CD36 acting as a lipid detector and GNAT3 acting as the α subunit of gustducin, a G protein governing sweet, savory, and bitter transduction. Strikingly, the genes encoding CD36 and GNAT3 are genomically superimposed, with CD36 completely encompassing GNAT3. To characterize genetic variation across the CD36-GNAT3 region, its implications for phenotypic diversity, and...
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