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Article

Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection

17 Dec 2021

Abstract excerpt

T cell immunity is crucial for control of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and has been studied widely on a quantitative level. However, the quality of responses, in particular of CD8 + T cells, has only been investigated marginally so far. Here, we isolate T cell receptor (TCR) repertoires specific for immunodominant SARS-CoV-2 epitopes restricted to common human Leukocyte...

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PMID: 34968416
DOI: 10.1016/j.celrep.2021.110214

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