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Article

Targeting the Proteostasis Network in Rhodopsin Retinitis Pigmentosa.

Advances in experimental medicine and biology - 1 Jan 2016

Parfitt David A, Cheetham Michael E

Abstract excerpt

Mutations in rhodopsin are one of the most common causes of retinitis pigmentosa (RP). Misfolding of rhodopsin can result in disruptions in cellular protein homeostasis, or proteostasis. There is currently no available treatment for RP. In this review, we discuss the different approaches currently being investigated for treatment of rhodopsin RP, focusing on the potential of manipulation of the proteostasis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26427449
DOI: 10.1007/978-3-319-17121-0_64
PMCID: PMC5042317

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