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Article

A Novel High-Throughput Nanopore-Sequencing-Based Strategy for Rapid and Automated S-Protein Typing of SARS-CoV-2 Variants.

Viruses - 19 Dec 2021

Wagner Gabriel E, Totaro Massimo G, Volland André, Lipp Michaela, Saiger Sabine, Lichtenegger Sabine, Forstner Patrick, von Laer Dorothee, Oberdorfer Gustav, Steinmetz Ivo

Abstract excerpt

Rapid molecular surveillance of SARS-CoV-2 S-protein variants leading to immune escape and/or increased infectivity is of utmost importance. Among global bottlenecks for variant monitoring in diagnostic settings are sequencing and bioinformatics capacities. In this study, we aimed to establish a rapid and user-friendly protocol for high-throughput S-gene sequencing and subsequent automated identification of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 34960817
DOI: 10.3390/v13122548
PMCID: PMC8704619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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