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EZH2 targeting to improve the sensitivity of acquired radio-resistance bladder cancer cells

21 Dec 2021

Abstract excerpt

Among the many treatments for Bladder cancer (BCa) patients, radiotherapy is an effective way to preserve the bladder. However, as the frequency of irradiation increases, the tumor cells appear "acquired radio-resistance" (ARR) and loss the sensitivity to radiotherapy. To explore the molecular mechanism of ARR, two BCa cell lines, 5637 and T24, were enrolled here and their ARR counterparts, 5637R and T24R, were...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 34952334
DOI: 10.1016/j.tranon.2021.101316

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