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Article

Genetic determinants for chemo- and radiotherapy resistance in bladder cancer

1 Dec 2017

Abstract excerpt

Bladder cancer (BCa) is burdened by high rates of chemo- and radio-resistance. We reviewed and summarized the current evidence regarding the genetic determinants of resistance in patients treated with chemotherapy and/or radiotherapy (RT) for BCa. Genetic heterogeneity may preexist to treatment arising with tumorigenesis or increasing progressively during the treatment. Several biological pathways seem to be...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 29354495
DOI: 10.21037/tau.2017.08.19

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