Association Between Interleukin 35 Gene Single Nucleotide Polymorphisms and the Uveitis Immune Status in a Chinese Han Population.

doi:10.3389/fimmu.2021.758554

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Article

Association Between Interleukin 35 Gene Single Nucleotide Polymorphisms and the Uveitis Immune Status in a Chinese Han Population.

Frontiers in immunology - 1 Jan 2021

Feng Meng, Zhou Shuping, Liu Tong, Yu Yong, Su Qinghong, Li Xiaofan, Zhang Min, Xie Xiao, Liu Tingting, Lin Wei

Abstract excerpt

Autoimmune uveitis is characterized by immune disorders of the eyes and the whole body and is often recurrent in young adults, but its pathogenesis is still unclear. IL-35 is an essential regulatory factor in many autoimmune diseases, which is produced by Breg cells and can induce Breg cells to regulate the immune response. The relationship between the expression and gene polymorphism of IL-35 and the immune...

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PMID: 34950136
DOI: 10.3389/fimmu.2021.758554
PMCID: PMC8688856

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