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Interleukin-17 gene polymorphism is associated with Vogt-Koyanagi-Harada syndrome but not with Behçet's disease in a Chinese Han population.

Human immunology - 1 Oct 2010

Shu Qinmeng, Yang Peizeng, Hou Shengping, Li Fuzhen, Chen Yuanyuan, Du Liping, Jiang Zhengxuan

Abstract excerpt

Interleukin (IL)-17 has been shown to play an important role in certain autoimmune diseases. The present study was performed to investigate the association of IL-17A and IL-17F gene polymorphisms with two autoimmune uveitis entities, Vogt-Koyanagi-Harada (VKH) syndrome and Behçet's disease (BD), in a Chinese Han population. A total of 362 BD patients, 385 VKH syndrome patients, and 412 controls were genotyped for...

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PMID: 20620187
DOI: 10.1016/j.humimm.2010.06.020

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