Genetic variants in candidate genes influencing NAFLD progression.

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder including simple steatosis and nonalcoholic steatohepatitis (NASH). Advanced stages of NASH result ultimately in fibrosis, cirrhosis, and hepatocarcinoma. A diagnosis of NASH entails an increased risk of both liver-related and cardiovascular mortality as worsening of the metabolic syndrome. Because of its escalation, many investigations have been...

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• Disease Progression
• Fatty Liver
• Genetic Linkage
• Lipid Metabolism
• Liver
• Metabolic Networks and Pathways