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Article

Mammalian Orthoreovirus Reassortment Proceeds with Little Constraint on Segment Mixing.

Journal of virology - 23 Feb 2022

Hockman Megan R, Jacobs Nathan T, Mainou Bernardo A, Koelle Katia, Lowen Anice C

Abstract excerpt

Segmentation of viral genomes provides the potential for genetic exchange within coinfected cells. However, for this potential to be realized, coinfecting genomes must mix during the viral life cycle. The efficiency of reassortment, in turn, dictates its potential to drive evolution. The opportunity for mixing within coinfected cells may vary greatly across virus families, such that the evolutionary implications...

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Identifiers

PMID: 34935439
DOI: 10.1128/JVI.01832-21
PMCID: PMC8865455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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