Article
Expression of Programmed Cell Death-L1 (PD-L1) Protein and Mismatch Repair Mutations in Orbital Tumours-a Pilot Study.
European journal of ophthalmology - 1 Sept 2022
AlSemari Mohammad A, Strianese Diego, Abu Safieh Leen, Al Hussain Hailah, Abedalthagafi Malak, Edward Deepak P
Abstract excerpt
PURPOSE: Programmed cell death protein 1 (PD-1) and DNA mismatch repair (MMR) deficiency play an important role in tumour progression and response to treatment.Both markers have been studied in some ocular tumours but little is known about these markers in orbital tumours. This pilot study reports on PD-L1 expression and MMR mutations using next generation sequencing (NGS) in specific orbital tumours. METHODS: We...
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