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Article

Mendelian Randomization Analysis Reveals Causal Effects of Plasma Proteome on Body Composition Traits.

The Journal of clinical endocrinology and metabolism - 19 Apr 2022

Han Bai-Xue, Yan Shan-Shan, Xu Qian, Ni Jing-Jing, Wei Xin-Tong, Feng Gui-Juan, Zhang Hong, Li Bin, Zhang Lei, Pei Yu-Fang

Abstract excerpt

CONTEXT: Observational studies have demonstrated associations between plasma proteins and obesity, but evidence of causal relationship remains to be studied. OBJECTIVE: We aimed to evaluate the causal relationship between plasma proteins and body composition. METHODS: We conducted a 2-sample Mendelian randomization (MR) analysis based on the genome-wide association study (GWAS) summary statistics of 23 body...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34922401
DOI: 10.1210/clinem/dgab911

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