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Phage ImmunoPrecipitation Sequencing (PhIP-Seq): The Promise of High Throughput Serology

11 May 2022

Abstract excerpt

Phage ImmunoPrecipitation Sequencing (PhIP-Seq) is a high throughput serological technology that is revolutionizing the manner in which we track antibody profiles. In this review, we mainly focus on its application to viral infectious diseases. Through the pull-down of patient antibodies using peptide-tile-expressing T7 bacteriophages and detection using next-generation sequencing (NGS), PhIP-Seq allows the...

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PMID: 35631089
DOI: 10.3390/pathogens11050568

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