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Ancient Demographics Determine the Effectiveness of Genetic Purging in Endangered Lizards.

Molecular biology and evolution - 7 Jan 2022

Xie Hong-Xin, Liang Xi-Xi, Chen Zhi-Qiang, Li Wei-Ming, Mi Chun-Rong, Li Ming, Wu Zheng-Jun, Zhou Xu-Ming, Du Wei-Guo

Abstract excerpt

The purging of deleterious alleles has been hypothesized to mitigate inbreeding depression, but its effectiveness in endangered species remains debatable. To understand how deleterious alleles are purged during population contractions, we analyzed genomes of the endangered Chinese crocodile lizard (Shinisaurus crocodilurus), which is the only surviving species of its family and currently isolated into small...

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Identifiers

PMID: 34919713
DOI: 10.1093/molbev/msab359
PMCID: PMC8788223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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