Article
Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex.
Nature communications - 21 Feb 2020
Grossen Christine, Guillaume Frédéric, Keller Lukas F, Croll Daniel
Abstract excerpt
Human activity has caused dramatic population declines in many wild species. The resulting bottlenecks have a profound impact on the genetic makeup of a species with unknown consequences for health. A key genetic factor for species survival is the evolution of deleterious mutation load, but how bottleneck strength and mutation load interact lacks empirical evidence. We analyze 60 complete genomes of six ibex...
Topics
- Animals
- Animals, Wild
- Computer Simulation
- Conservation of Natural Resources
- Evolution, Molecular
- Genetic Variation
- Genetics, Population
- Genome
- Goats
- Models, Genetic
- Mutation