Article
A Novel PAX3 Variant in a Chinese Pedigree with Nonsyndromic Cleft Lip With or Without Palate.
Genetic testing and molecular biomarkers - 1 Dec 2021
Liang Wei, Huang Wenbin, Sun Bohui, Zhong Wenjie, Zhang Yunfan, Zhang Jieni, Zhou Zhibo, Lin Jiuxiang, Chen Feng
Abstract excerpt
Objectives: Nonsyndromic cleft lip with or without palate (NSCL/P) is a common congenital orofacial defect, which is associated with severe disruption of orofacial development. The present study was designed to identify potential underlying gene variants in a Chinese pedigree with NSCL/P, in which the proband and the proband's father were affected. Methods: DNA was extracted from the participants' peripheral...
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