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Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells

16 Dec 2021

Abstract excerpt

Although particle therapy with protons has proven to be beneficial in the treatment of chondrosarcoma compared to photon-based (X-ray) radiation therapy, the cellular and molecular mechanisms have not yet been sufficiently investigated. Cell viability and colony forming ability were analyzed after X-ray and proton irradiation (IR). Cell cycle was analyzed using flow cytometry and corresponding regulator genes and...

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PMID: 34916568
DOI: 10.1038/s41598-021-03529-9

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