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Sensitization of chondrosarcoma cells with PARP inhibitor and high-LET radiation

20 Jun 2019

Abstract excerpt

Chondrosarcoma is a malignant tumor that arises from cartilaginous tissue and is radioresistant and chemoresistant to conventional treatments. The preferred treatment consists of surgical resection, which might cause severe disabilities for the patient; in addition, this procedure might be impossible for inoperable locations, such as the skull base. Carbon ion irradiation (hadron therapy) has been proposed as an...

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PMID: 31312595
DOI: 10.1016/j.jbo.2019.100246

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