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Article

Use of Sanger protocols to identify variants of concern, key mutations and track evolution of SARS-CoV-2.

Journal of virological methods - 1 Feb 2022

Cabral Gabriela Bastos, Ahagon Cintia Mayumi, de Souza Guimarães Paula Morena, Silva Lopez-Lopes Giselle Ibette, Hussein Igor Mohamed, Cilli Audrey, de Jesus Alves Ivy, Coelho Bombonatte Andréa Gobetti, do Carmo Sampaio Tavares Timenetsky Maria, da Silva Santos Jaqueline Helena, de Oliveira Santos Katia Corrêa, Dos Santos Fabiana Cristina Pereira, de Macedo Brígido Luís Fernando

Abstract excerpt

Vaccination and the emergence of SARS-CoV-2 variants mark the second year of the pandemic. Variants have amino acid mutations at the spike region, a viral protein central in the understanding of COVID-19 pathogenesis and vaccine response. Variants may dominate local epidemics, as Gamma (P.1) in Brazil, emerging in 2020 and prevailing until mid-2021. Different obstacles hinder a wider use of Next-Generation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34915086
DOI: 10.1016/j.jviromet.2021.114422
PMCID: PMC8667421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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