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A Pan-Cancer Immunogenomic Atlas for Immune Checkpoint Blockade Immunotherapy

13 Dec 2021

Abstract excerpt

Abstract The ability to identify robust genomic signatures that predict response to immune checkpoint blockade is restricted by limited sample sizes and ungeneralizable performance across cohorts. To address these challenges, we established Cancer-Immu (http://bioinfo.vanderbilt.edu/database/Cancer-Immu/), a comprehensive platform that integrates large-scale multidimensional omics data, including genetic, bulk,...

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PMID: 34903605
DOI: 10.1158/0008-5472.can-21-2335

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