Article
[Effect of RITA on TP53 Mutant Human Mantle Cell Lymphoma Cell Line and Its Mechanism].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2021
Hua Jia-Ye, Zhou Xu-Hong, Wang Yan, Xu Bing
Abstract excerpt
OBJECTIVE: To investigate the effect of RITA on TP53 mutant human mantle cell lymphoma (MCL) cell line Mino and its possible mechanism. METHODS: Mino cells were cultured in RPMI-1640 and treated with RITA at a concentration of 0-16 μmol/L for 24,48,72 hours. Cell viability was assessed by CCK-8 assay. The cells were treated by RITA (0-8 μmol/L) for 48 h, the cell apoptosis induced by RITA was detected by annexin...
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