Article
SGT1-Specific Domain Mutations Impair Interactions with the Barley MLA6 Immune Receptor in Association with Loss of NLR Protein.
Molecular plant-microbe interactions : MPMI - 1 Mar 2022
Chapman Antony V E, Elmore J Mitch, McReynolds Maxwell, Walley Justin W, Wise Roger P
Abstract excerpt
The Mla (Mildew resistance locus a) of barley (Hordeum vulgare L.) is an effective model for cereal immunity against fungal pathogens. Like many resistance proteins, variants of the MLA coiled-coil nucleotide-binding leucine-rich repeat (CC-NLR) receptor often require the HRS complex (HSP90, RAR1, and SGT1) to function. However, functional analysis of Sgt1 has been particularly difficult, as deletions are often...
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