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Article

Synergistic epistasis of the deleterious effects of transposable elements.

Genetics - 4 Feb 2022

Lee Yuh Chwen G

Abstract excerpt

The replicative nature and generally deleterious effects of transposable elements (TEs) raise an outstanding question about how TE copy number is stably contained in host populations. Classic theoretical analyses predict that, when the decline in fitness due to each additional TE insertion is greater than linear, or when there is synergistic epistasis, selection against TEs can result in a stable equilibrium of...

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Identifiers

PMID: 34888644
DOI: 10.1093/genetics/iyab211
PMCID: PMC9097265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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