Article
DNA Repair Genes as Drug Candidates for Early Breast Cancer Onset in Latin America: A Systematic Review.
International journal of molecular sciences - 2 Dec 2021
Urbina-Jara Laura Keren, Martinez-Ledesma Emmanuel, Rojas-Martinez Augusto, Rodriguez-Recio Francisco Ricardo, Ortiz-Lopez Rocio
Abstract excerpt
The prevalence of breast cancer in young women (YWBC) has increased alarmingly. Significant efforts are being made to elucidate the biological mechanisms concerning the development, prognosis, and pathological response in early-onset breast cancer (BC) patients. Dysfunctional DNA repair proteins are implied in BC predisposition, progression, and therapy response, underscoring the need for further analyses on DNA...
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