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Article

Sequence duplication in 3' UTR modulates virus replication and virulence of Japanese encephalitis virus.

Emerging microbes & infections - 1 Dec 2022

Zhang Qiu-Yan, Liu Si-Qing, Li Xiao-Dan, Li Jia-Qi, Zhang Ya-Nan, Deng Cheng-Lin, Zhang Hong-Lei, Li Xu-Fang, Fang Chun-Xiao, Yang Feng-Xia, Zhang Bo, Xu Yi, Ye Han-Qing

Abstract excerpt

Japanese encephalitis virus (JEV), an important neurotropic pathogen, belongs to the genus Flavivirus of the family Flaviviridae and has caused huge threat to public health. It is still obscure regarding the functions of stem-loop (SL) and dumbbell (DB) domains of JEV 3' UTR in viral replication and virulence. In the current study, using the infectious clone of JEV SA14 strain as a backbone, we constructed a...

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Identifiers

PMID: 34877923
DOI: 10.1080/22221751.2021.2016354
PMCID: PMC8725919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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