Article
Nucleotide variations in 3' untranslated region contribute to the enhanced virulence and replication efficiency of reemerging Japanese encephalitis virus genotype V.
Virulence - 1 Dec 2026
Xia Qiqi, Zhang Yan, Zheng Jiayang, Liu Ke, Li Beibei, Li Zongjie, Shao Donghua, Qiu Yafeng, Ma Zhiyong, Wei Jianchao
Abstract excerpt
Japanese encephalitis virus, a major causative agent of viral encephalitis in Asia, is classified into five genotypes. Genotype V (GV) has reemerged after more than 50 years of apparent absence, following identification of the sole GV isolate - the Muar strain - in 1952. Newly reemerged GV strains are genetically distinct from the ancestral Muar strain. In this study, we compared virulence and replication...
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