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Article

Half a Century Tales of Familial Hypercholesterolemia (FH) in Japan.

Journal of atherosclerosis and thrombosis - 1 Mar 2017

Mabuchi Hiroshi

Abstract excerpt

Familial hypercholesterolemia (FH) is a disease characterized by a triad: elevated low-density lipoprotein (LDL) cholesterol, tendon xanthomas, and premature coronary heart disease. Thus, it can be considered as a model disease for hypercholesterolemia and atherosclerotic cardiovascular disease (ASCVD). For the diagnosis of hetero-FH, the detection of Achilles tendon xanthomas by palpation or on X-ray is an...

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Identifiers

PMID: 28179607
DOI: 10.5551/jat.RV16008
PMCID: PMC5383536

Genes

PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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