Apolipoprotein E modulates auditory event-related potentials in healthy aging.

doi:10.1016/j.neulet.2009.04.053

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Article

Apolipoprotein E modulates auditory event-related potentials in healthy aging.

Neuroscience letters - 7 Aug 2009

Espeseth Thomas, Rootwelt Helge, Reinvang Ivar

Abstract excerpt

42 individuals ranging from 47 to 73 years of age underwent an auditory three-stimulus oddball task while their event-related potentials (ERPs) were recorded. Half were APOE epsilon3 homozygotes and the remaining participants were either epsilon3/epsilon4 heterozygotes (n=13), or epsilon4 homozygotes (n=8). Analyses of variance showed that the heterozygotes had lower N1 amplitudes than the epsilon3 homozygotes,...

Topics

Acoustic Stimulation
Aged
Aging
Analysis of Variance
Apolipoprotein E3
Apolipoprotein E4
Brain
Electroencephalography
Evoked Potentials, Auditory
Female
Follow-Up Studies
Genotype
Humans
Learning Disabilities
Male
Middle Aged
Neuropsychological Tests
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 19409447
DOI: 10.1016/j.neulet.2009.04.053

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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