Article
Building the What Comes Next Cohort for BRCA1 and BRCA2 testing: a descriptive analysis.
CMAJ open - 1 Jan 2000
Dossa Fahima, Metcalfe Kelly, Sutradhar Rinku, Little Tari, Eisen Andrea, Chun Kathy, Meschino Wendy S, Velsher Lea, Ellis Jordan Lerner, Baxter Nancy N
Abstract excerpt
BACKGROUND: Our understanding of how testing for and mutations of the BRCA1 and BRCA2 genes affect cancer risk and the use of risk-reduction strategies comes largely from studies of women recruited from specialized genetics clinics. Our aim was to assemble a generalizable cohort of women who underwent BRCA1/BRCA2 testing (the What Comes Next Cohort), irrespective of test result, to enable study of health care...
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