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BRCA1/2 testing for genetic susceptibility to cancer after 25 years: A scoping review and a primer on ethical implications.

Breast (Edinburgh, Scotland) - 1 Feb 2022

Petrova Dafina, Cruz Maite, Sánchez María-José

Abstract excerpt

BACKGROUND: Mutations in the genes called BRCA1 and BRCA2 are associated with significantly elevated lifetime risk of developing breast and ovarian cancer. This year marks 25 years since genetic tests for BRCA1/2 mutations became available to the public. Currently, comprehensive guidelines exist regarding BRCA1/2 testing and preventive measures in mutation carriers. As such, BRCA1/2 testing represents a precedent...

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Identifiers

PMID: 34920368
DOI: 10.1016/j.breast.2021.12.005
PMCID: PMC8686063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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