Article
Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population.
Journal of medical genetics - 1 Aug 2018
Manchanda Ranjit, Blyuss Oleg, Gaba Faiza, Gordeev Vladimir Sergeevich, Jacobs Chris, Burnell Matthew, Gan Carmen, Taylor Rohan, Turnbull Clare, Legood Rosa, Zaikin Alexey, Antoniou Antonis C, Menon Usha, Jacobs Ian
Abstract excerpt
BACKGROUND: BRCA carrier identification offers opportunities for early diagnoses, targeted treatment and cancer prevention. We evaluate BRCA- carrier detection rates in general and Ashkenazi Jewish (AJ) populations across Greater London and estimate time-to-detection of all identifiable BRCA carriers. METHODS: BRCA carrier data from 1993 to 2014 were obtained from National Health Service genetic laboratories and...
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