Article
Suboptimal Adherence to Hereditary Cancer Risk Management Guidelines: A Cohort Study of High-Risk Individuals in Newfoundland and Labrador, Canada.
Current oncology (Toronto, Ont.) - 26 Mar 2026
Etchegary Holly, Puddester Rebecca, Gao Zhiwei, Francis Vanessa, Warren Mike, Burry T Nadine, Seal Melanie, Woods Michael, Watkins Kathy, Pike April, Avery Susan, McGrath Jerry, MacMillan Andree, Dawson Lesa
Abstract excerpt
Hereditary cancer syndromes (HCSs), including BRCA 1/2-associated hereditary breast and ovarian cancer (HBOC) and Lynch syndrome (LS), confer substantial lifetime cancer risks, yet adherence to recommended risk-management strategies remains variable. This population-based retrospective cohort study examined cancer prevention practices, outcomes, and predictors of cancer occurrence among 476 BRCA and LS carriers...
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