Article
Genetic liability for prescription opioid use and risk of cardiovascular diseases: a multivariable Mendelian randomization study.
Addiction (Abingdon, England) - 1 May 2022
Cai Jiahao, He Lei, Wang Hongxuan, Rong Xiaoming, Chen Ming, Shen Qingyu, Li Xiangpen, Li Mei, Peng Ying
Abstract excerpt
BACKGROUND AND AIMS: Observational studies have yielded conflicting results on the association of prescription opioid use (POU) with the risk of cardiovascular diseases (CVD). Residual confounding and potential reverse causality are inevitable in such conventional observational studies. This study used Mendelian randomization (MR) design to estimate the causal effect of POU on the risk of CVD, including coronary...
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