Article
Maternal Polycystic Ovary Syndrome and Offspring Birth Weight: A Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism - 24 Mar 2022
Gan Yuexin, Lu Donghao, Yan Chonghuai, Zhang Jun, Zhao Jian
Abstract excerpt
CONTEXT: Observational associations between maternal polycystic ovary syndrome (PCOS) and offspring birth weight (BW) have been inconsistent and the causal relationship is still uncertain. OBJECTIVE: We conducted a 2-sample Mendelian randomization (MR) study to estimate the causal effect of maternal PCOS on offspring BW. METHODS: We constructed genetic instruments for PCOS with 14 single nucleotide polymorphisms...
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