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Article

Functional dissection of the C. elegans cell adhesion molecule SAX-7, a homologue of human L1.

Molecular and cellular neurosciences - 1 Jan 2008

Pocock Roger, Bénard Claire Y, Shapiro Lawrence, Hobert Oliver

Abstract excerpt

Cell adhesion molecules of the Immunoglobulin superfamily (IgCAMs) play important roles in neuronal development, homeostasis and disease. Here, we use an animal in vivo assay system to study the function of sax-7, the Caenorhabditis elegans homologue of the human L1 IgCAM, a homophilic adhesion molecule involved in several neurological diseases. We show that the 6 Ig/5 FnIII domain protein SAX-7 acts autonomously...

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PMID: 17933550
DOI: 10.1016/j.mcn.2007.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional dissection of the C. elegans cell adhesion molecule SAX-7, a homologue of human L1.PMID 17933550Read ↗

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