Mitochondria-Targeted Compounds to Assess and Improve Human Sperm Function

Abstract excerpt

Significance: Currently 10%–15% of couples in reproductive age face infertility issues. More importantly, male factor contributes to 50% of these cases (either alone or in combination with female causes). Among various reasons, impaired sperm function is the main cause for male infertility. Furthermore, mitochondrial dysfunction and oxidative stress due to increased reactive oxygen species (ROS) production,...

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