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Age-Related Decline of Male Fertility: Mitochondrial Dysfunction and the Antioxidant Interventions

23 Apr 2022

Abstract excerpt

Mitochondria are structurally and functionally unique organelles in male gametes. Apparently, as the only organelles remaining in mature sperm, mitochondria not only produce adeno-sine triphosphate (ATP) through oxidative phosphorylation (OXPHOS) to support sperm mobility, but also play key roles in regulating reactive oxidation species (ROS) signaling, calcium homeostasis, steroid hormone biosynthesis, and...

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PMID: 35631346
DOI: 10.3390/ph15050519

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