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Mitochondrial Functionality in Male Fertility: From Spermatogenesis to Fertilization

12 Jan 2021

Abstract excerpt

Mitochondria are structurally and functionally distinct organelles that produce adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to spermatozoa. They can also produce reactive oxidation species (ROS). While a moderate concentration of ROS is critical for tyrosine phosphorylation in cholesterol efflux, sperm-egg interaction, and fertilization, excessive ROS generation is...

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PMID: 33445610
DOI: 10.3390/antiox10010098

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