Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophages and Monocytes: “Trojan Horses” in COVID-19

28 Oct 2021

Abstract excerpt

We aimed to explore whether variants of SARS-CoV-2 (Chinese-derived strain (D614, lineage A), Italian strain PV10734 (D614G, lineage B.1.1) and Alpha strain (lineage B.1.1.7)) were able to infect monocytes (MN) and monocyte-derived macrophages (MDM) and whether these infected cells may, in turn, be vectors of infection. For this purpose, we designed an in vitro study following the evolution of MN and MDM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to COVID-19 epidemiological studies
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34834984
DOI: 10.3390/v13112178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophages and Monocytes: “Trojan Horses” in COVID-19PMID 34834984Read ↗

Monocytes and Macrophages as Viral Targets and ReservoirsSemantic proximity Read ↗

Primary macrophages exhibit a modest inflammatory response early in SARS-CoV-2 infectionSemantic proximity Read ↗

A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV2 at the immune-epithelial interfaceSemantic proximity Read ↗

A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interfaceSemantic proximity Read ↗

Decades Long Involvement of THP-1 Cells as a Model for Macrophage Research: A Comprehensive ReviewSemantic proximity Read ↗

SARS-CoV-2 B.1.1.7 lineage rapidly spreads and replaces R.1 lineage in Japan: Serial and stationary observation in a communitySemantic proximity Read ↗

Interaction of Coxiella burnetii Strains of Different Sources and Genotypes with Bovine and Human Monocyte-Derived Macrophages.Semantic proximity Read ↗

The original strain of SARS-CoV-2, the Delta variant, and the Omicron variant infect microglia efficiently, in contrast to their inability to infect neurons: Analysis using 2D and 3D culturesSemantic proximity Read ↗

Monocytes and infection: modulator, messenger and effector.Semantic proximity Read ↗

CA-CAS-01-A: A Permissive Cell Line for Isolation and Live Attenuated Vaccine Development Against African Swine Fever VirusSemantic proximity Read ↗

Myeloid Cell Interaction with HIV: A Complex RelationshipSemantic proximity Read ↗

Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.