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Article

Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia.

Cells - 22 Nov 2021

Schmitner Nicole, Recheis Christina, Thönig Jakob, Kimmel Robin A

Abstract excerpt

Diabetic retinopathy is a frequent complication of longstanding diabetes, which comprises a complex interplay of microvascular abnormalities and neurodegeneration. Zebrafish harboring a homozygous mutation in the pancreatic transcription factor pdx1 display a diabetic phenotype with survival into adulthood, and are therefore uniquely suitable among zebrafish models for studying pathologies associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34831487
DOI: 10.3390/cells10113265
PMCID: PMC8622914

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