Article
Cell-Free DNA Variant Sequencing Using Plasma and AR-V7 Testing of Circulating Tumor Cells in Prostate Cancer Patients.
Cells - 18 Nov 2021
Lieb Verena, Abdulrahman Amer, Weigelt Katrin, Hauch Siegfried, Gombert Michael, Guzman Juan, Bellut Laura, Goebell Peter J, Stöhr Robert, Hartmann Arndt, Wullich Bernd, Taubert Helge, Wach Sven
Abstract excerpt
Prostate cancer (PCa) is the second most common malignant cancer and is a major cause of morbidity and mortality among men worldwide. There is still an urgent need for biomarkers applicable for diagnosis, prognosis, therapy prediction, or therapy monitoring in PCa. Liquid biopsies, including cell-free DNA (cfDNA) and circulating tumor cells (CTCs), are a valuable source for studying such biomarkers and are...
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