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Genetic Variability of the Functional Domains of Chromodomains Helicase DNA-Binding (CHD) Proteins.

Genes - 19 Nov 2021

Cardoso Ana R, Lopes-Marques Mónica, Oliveira Manuela, Amorim António, Prata Maria J, Azevedo Luísa

Abstract excerpt

In the past few years, there has been an increasing neuroscientific interest in understanding the function of mammalian chromodomains helicase DNA-binding (CHD) proteins due to their association with severe developmental syndromes. Mammalian CHDs include nine members (CHD1 to CHD9), grouped into subfamilies according to the presence of specific functional domains, generally highly conserved in evolutionary terms....

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PMID: 34828433
DOI: 10.3390/genes12111827
PMCID: PMC8623811

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