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Article

Associations of Polymorphisms Localized in the 3'UTR Regions of the KRAS, NRAS, MAPK1 Genes with Laryngeal Squamous Cell Carcinoma.

Genes - 23 Oct 2021

Insodaite Ruta, Smalinskiene Alina, Liutkevicius Vykintas, Ulozas Virgilijus, Poceviciute Roberta, Bielevicius Arunas, Kucinskas Laimutis

Abstract excerpt

BACKGROUND: Genetic variations, localized in the 3' untranslated region (UTR) in mitogen-activated protein kinase (MAPK) pathway-related genes, may alter the transcription and impact the pathogenesis of laryngeal squamous cell carcinoma (LSCC). The present study investigated the associations of single-nucleotide polymorphisms (SNP), localized in the 3'UTR) of the KRAS, NRAS, and MAPK1 genes with LSCC risk and...

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Identifiers

PMID: 34828284
DOI: 10.3390/genes12111679
PMCID: PMC8625477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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