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Article

Regulatory Single Nucleotide Polymorphism of the Bovine IFITM3 Gene Induces Differential Transcriptional Capacities of Hanwoo and Holstein Cattle.

Genes - 21 Oct 2021

Kim Yong-Chan, Jeong Min-Ju, Jeong Byung-Hoon

Abstract excerpt

Interferon-induced transmembrane protein 3 (IFITM3), a crucial effector of the host's innate immune system, prohibits an extensive range of viruses. Previous studies have reported that single nucleotide polymorphisms (SNPs) of the IFITM3 gene are associated with the expression level and length of the IFITM3 protein and can impact susceptibility to infectious viruses and the severity of infection with these...

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Identifiers

PMID: 34828268
DOI: 10.3390/genes12111662
PMCID: PMC8619045

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