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Article

Transcriptomic Analysis of Cardiomyocyte Extracellular Vesicles in Hypertrophic Cardiomyopathy Reveals Differential snoRNA Cargo.

Stem cells and development - 15 Dec 2021

James Victoria, Nizamudeen Zubair A, Lea Daniel, Dottorini Tania, Holmes Terri L, Johnson Benjamin B, Arkill Kenton P, Denning Chris, Smith James G W

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is characterized by increased left ventricular wall thickness that can lead to devastating conditions such as heart failure and sudden cardiac death. Despite extensive study, the mechanisms mediating many of the associated clinical manifestations remain unknown and human models are required. To address this, human-induced pluripotent stem cell (hiPSC) lines were generated from...

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Share to Cardiomyopathy and Myosin Studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Induced Pluripotent Stem Cells

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Source

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Identifiers

PMID: 34806414
DOI: 10.1089/scd.2021.0202
PMCID: PMC8742282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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